Femara is available in generic form. Letrozole oral tablets can interact with several types of drugs. "Product Information. Recently, it has been utilized in infertile pre-menopausal women because of its ability to enhance FSH production for ovulation induction. The most common side-effects of treatment are hot flushes, sweating, joint pain, and feeling tired. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). So, check with your doctor about the dosage of letrozole for infertility thats recommended for you. This is not a complete list of side effects and others may occur. This may raise the chance of broken bones. A healthy diet and exercise can help lower your cholesterol. If its hard for you to read the label on your prescription, tell your doctor or pharmacist. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Letrozole may also make you feel sick (nausea) or be sick (vomiting). A lack of oestrogen over time can causeosteoporosis. Melatonin and Breast Cancer: Is it Safe and Can it Help? Other side effects Is there anything I can do or any supplements I can take to help prevent this? , . To learn about other mild side effects, talk with your doctor or pharmacist, or read letrozole oral tablets prescribing information. If youre using letrozole for fertility, follow your healthcare providers instructions carefully on when to start and stop the medication. Its important to discuss all your concerns with your doctor. Do not use if you are pregnant. The stress of the breast cancer and the initial treatment, whether it was surgery, chemo (with steroids of course), radiotherapy or all 3 will have contributed to raised levels at the time. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Letrozole is the generic version of the brand-name drug Femara. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Letrozole comes as oral tablets that youll take by mouth. More than 25% of people reported joint pain in letrozoles clinical trials. Take calcium and vitamin D as you were told by your doctor. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Phytoestrogens act like estrogen in the body. What Types of Breast Cancer Have the Highest Recurrence Rates? Will any of my current medications interact with letrozole? Letrozole may cause dizziness. Some of these can happen when common side effects go unchecked: Bone fractures: As discussed above, bone loss that happens with the long-term use of letrozole can lead to bone fractures. They work by killing cells in your body that quickly multiply (make more cells). You may report them to the FDA. If you have any worries or questions about taking or stopping letrozole, you can call us free on 0808 800 6000 to talk through your concerns. Written by Cerner Multum. Many treatments are available for a yeast infection, some of which a person can administer at home. But it can treat other forms of infertility, as well. Letrozole may also be used for purposes not listed in this medication guide. Certain pharmacies provide medication labels that: Your doctor or pharmacist may be able to recommend a pharmacy that offers these options if your current pharmacy doesnt. During studies of letrozole, headaches were a common side effect in people taking the drug. Rabaglio, M., et al. I was checked for an infection but that came back clear. In some cases, letrozole is prescribed for early breast cancer thats already been treated with surgery plus 5 years of tamoxifen therapy. Common side effects If you have a certain type of breast cancer, your doctor may prescribe letrozole oral tablets for you. * In this article, we use the term female to refer to someones sex assigned at birth. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. letrozole is for use only in women who can no longer get pregnant. You may have menopausal symptoms such as hot flushes, sweating, sleep disturbance, vaginal irritation such as dryness and itching, and reduced libido (sex drive). q. When used for treatment, both tamoxifen and aromatase inhibitors can lead to vaginal dryness, itching, irritation, painful intercourse, painful urination, or recurrent urinary tract infections. This is why chemotherapy can cause hair loss and many other side effects. Small cuts or tiny cracks in the skin of your vulva because of fragile skin in the area. Letrozole and other drugs in the same group of medications commonly cause joint pain and stiffness. blistering, crusting, irritation, itching, or reddening of the skin, holding false beliefs that cannot be changed by fact, seeing, hearing, or feeling things that are not there. The most common side effect of letrozole is high cholesterol. More serious side effects are possible, including bone fractures and complications from high cholesterol. When this happens before menopause, it causes a higher release of other hormones necessary for fertility. Stopping smoking and doing regular weight-bearing exercise can also help keep your bones strong. You may have questions about letrozole oral tablets and your treatment plan. (When you ovulate, an egg is released from your ovaries). Many people find that symptoms improve over time. Muscle and joint pain is the most common reason that people decide to stop using letrozole. As mentioned above, low estrogen levels can lead to bone loss. There's no way to completely predict or prevent breast cancer. Store at room temperature away from moisture and heat. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. What should be considered before taking letrozole? You may have some side effects very quickly. You may also want to check out the online communities at Bezzy. For vitamin D, you can increase the amount of oily fish, mushrooms and eggs you eat. Heart attack or stroke: Over time, high cholesterol can raise your risk of more serious complications like a heart attack or stroke. What Are Side Effects of Femara? Medically reviewed by Drugs.com on May 4, 2022. GoodRx is not sponsored by or affiliated with any of the third-party brands identified. You should always consult your doctor or another healthcare professional before taking any medication. This enzyme changes androgen hormones (like testosterone) found in skin, muscle, and fat cells into estrogen. By taking proactive steps, like healthy eating and exercise, you may be able to prevent or manage weight gain from letrozole. You may wish to discuss this with your treatment team or GP, or ask the pharmacist who dispenses your prescriptions if they can supply you with letrozole from the manufacturer you feel suits you the best. It is also used for women who have already had other cancer treatments (eg, tamoxifen). (2022). Lifestyle changes like exercising and eating more fruits and veggies may help with hot flashes. The study uses data from the FDA. Along with its needed effects, oxybutynin (the active ingredient contained in Oxytrol) may cause some unwanted effects. These and other important considerations are discussed in detail below. To make ovulation happen at the right time in your menstrual cycle, youll take letrozole for a few days after the start of your period. The active ingredient in OXYTROL, oxybutynin, can cause swelling around the eyes, lips, genitals, hands or feet. Tell your doctor about all your current medicines and any medicine you start or stop using. There are CDs, podcasts and phone apps that can guide you through these techniques. 2. If the bleeding continues for more than a few days, tell your specialist. Unlike letrozole, clomiphene is approved for this use. Like any drug,letrozolecan cause side effects. But sometimes, metformin is given together with clomiphene to help treat infertility in females with PCOS. 31 Aug 2021 13:51 in response to EllieJ. How Letrozole Is Given: Letrozole is a pill, taken by mouth. In studies, joint pain was a common side effect of letrozole. PCT is used to help minimize side effects that bodybuilders have when they take anabolic steroids to build muscles. If you feel dizzy, avoid driving. You may take letrozole with or without food. Letrozole may cause weight gain. Its also not recommended to use letrozole while nursing because safety and efficacy studies are lacking. You can unsubscribe at any time. A small number of women notice an increase in downy facial hair. You should not use letrozole if you are allergic to it. Be sure to follow your doctors instructions. If your appetite increases it may affect your weight. If youd like more information about how letrozole compares with Arimidex, see this detailed breakdown. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our. These websites also offer tools to help you find low-cost healthcare and certain educational resources. Metformin is a drug thats typically used to treat diabetes. Nicole E. Cieri-Hutcherson, PharmD, BCPS, NCMP. If you notice this or any other swelling, let your GP know. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Continue reading, You can take letrozole (Femara) in the morning or evening, but you should take it at about the same time each day. oxybutynin, Myrbetriq, Botox, phenazopyridine, Pyridium, solifenacin, tolterodine, Detrol, VESIcare, Ditropan. Common letrozole side effects include hot flashes, night sweats, and muscle or joint pain. Letrozole oral tablets may not be right for you if you have certain medical conditions or other factors that affect your health. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Letrozole resulted in an increased volume percentage of collagens and decreased bladder compliance. If fatigue happens while youre using letrozole, try taking your dose at night. Call 911 or seek emergency medical care if you notice symptoms of a serious letrozole side effect. Your GP or specialist can refer you for counselling or may suggest you take an antidepressant drug. It is used to treat breast cancer in women who have gone through menopause. Costs of prescription drugs can vary depending on many factors. Around 6% experienced weight loss. Side effects tend to go away once letrozole is stopped. You should not use letrozole if you are pregnant. Bone fractures: Sudden pain, swelling, or trouble moving a limb may be signs of a bone fracture. If you are having difficulty accessing this website, please call or email us at (855) 268-2822 or ada@goodrx.com so that we can provide you with the services you require through alternative means. Of infertility, as well unlike letrozole, headaches were a common side effect in taking! Or stroke: Over time, high cholesterol can raise your risk more! From letrozole is prescribed for early breast cancer in women who have already had other cancer treatments (,. 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